Carlisle is about 190 miles from me here at the NJ Shore, so I imagine Paul is about the same plus or minus 10 miles or so.
Because he’s farther north in NJ, Paul’s route to Carlisle takes him west on I-78 to I-81.
I am almost in the exact center of NJ on the Atlantic coast. My route to Carlise is west on I-195 to US 1 to the PA Turnpike (I-76).
Carlisle is where I-76 and I-81 intersect. It’s about 3 hours for me.